Abel Prize for randomness mathematician Michel Talagrand

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An image from NASA's Mars Perseverance rover taken while it drills for rock samples.

The Perseverance rover drills a rock core from the sting of the traditional river delta in Jezero Crater on Mars.Credit score: NASA/JPL-Caltech

NASA is dealing with some powerful questions amid price range woes: the place ought to its Mars rover Perseverance gather its closing rock samples — and can it even be capable of afford to fly them dwelling? Bringing Perseverance’s valuable samples again to Earth might price as a lot as US$11 billion. Perseverance’s crew can also be debating whether or not to alter the rover’s journey plans to save lots of prices. “My focus is de facto on ensuring that we get as a lot science out of what we are able to get,” says NASA’s Lindsay Hays.

Nature | 7 min learn

For the primary time, a synthetic intelligence (AI) system has helped researchers to design utterly new antibodies. Creating new variations of those immune proteins, which can be utilized as medication, is normally a prolonged and dear course of. An AI algorithm much like these of the image-generating instruments Midjourney and DALL·E was skilled on hundreds of real-world constructions of antibodies connected to their goal proteins. It then churned out hundreds of latest antibodies that acknowledge sure bacterial, viral or cancer-related targets. Though in laboratory exams solely about one in 100 designs labored as hoped, biochemist and research co-author Joseph Watson says that “it looks like fairly a landmark second”.

Nature | 4 min learn

Reference: bioRxiv preprint (not peer reviewed)

The winner of this 12 months’s Abel arithmetic prize, Michel Talagrand, developed formulae to make random processes extra predictable. He confirmed that the contributions of many variables that affect processes comparable to a river’s water degree usually cancel one another out — making the general consequence much less variable, no more. Talagrand, who’s retired, likes to problem his fellow mathematicians: he retains an inventory of issues on his web site, providing money to those that remedy it so long as he’s “not too senile to know the proofs I obtain”.

Nature | 6 min learn

Why is Earth so scorching proper now?

Report warmth defies all predictions

We knew that Earth is heating up. However not this a lot. “For the previous 9 months, imply land and sea floor temperatures have overshot earlier data every month by as much as 0.2 °C — an enormous margin on the planetary scale,” writes Gavin Schmidt, the director of NASA’s Goddard Institute for Area Research. “It’s humbling, and a bit worrying, to confess that no 12 months has confounded local weather scientists’ predictive capabilities greater than 2023 has.”

A number of elements may need contributed, in addition to the greenhouse gases we proceed pumping into the ambiance: the beginning of the El Niño climate sample, fallout from the 2022 volcanic eruption in Tonga and a ramp-up of photo voltaic exercise. However, even after taking all believable explanations under consideration, statistical local weather fashions are struggling to elucidate what’s taking place. The fear is {that a} warming planet is “already basically altering how the local weather system operates, a lot before scientists had anticipated”.

Nature | 5 min learn

Infographic of the week

An infographic in two parts. The first image shows a partridge running up a steep slope, its wings folded. The second image shows the same bird running up a near-vertical surface while spreading its wings.

Fifty years in the past, palaeontologist John Ostrom proposed that birds developed from small, bipedal dinosaurs somewhat than from tree-dwelling animals. He reframed the talk in regards to the origin of flight by specializing in its biomechanics. His concepts had been later examined and supported by work — together with a 2003 research on chukar partridges (Alectoris chukar) — which confirmed that wing motion can create a vortex that helps the animal to run up vertical slopes. (Nature Information & Views | 8 min learn, Nature paywall)

Reference: Quarterly Overview of Biology paper (from 1974)

Options & opinion

Cartoon animation showing a cowboy riding a protein structure in a rotoscope-style.

Illustration: Fabio Buonocore

Time-resolved cryo-electron microscopy is popping nonetheless pictures of the tiny motors and units that energy life into movement photos. Biomolecules are in fixed movement, and capturing this motion will help scientists to unravel dynamic processes comparable to how a muscle protein generates power or how a plant virus infects a cell to launch its genetic materials. There are numerous methods of making these films, for instance freezing samples and utilizing laser pulses to reanimate them for just a few microseconds earlier than they refreeze. The method is “fussy and arduous to manage”, says structural biologist Bridget Carragher. However there is no such thing as a scarcity of attention-grabbing questions for scientists to sort out with it proper now

Nature | 9 min learn

A cyberattack can imply shedding valuable or delicate recordsdata, comparable to well being data, or having to pay a ransom to regain entry to them. To stop this from taking place, “replace your software program often; implement firewall and antivirus options; management entry and permissions to your methods; encrypt delicate information”, says information-technology specialist Ildeberto Aparecido Rodello. If you happen to’ve been hacked, “pull out the plugs and shut it down”, advises information-security knowledgeable Sarah Lawson. “Shut it after which search recommendation.”

Nature | 8 min learn

Quote of the day

Olugbenga Samuel Oyeniyi explains how he went from a scientific scientist dreaming of discovering a treatment for malaria to working in public well being with a concentrate on prostate most cancers. (Nature | 6 min learn)

At this time I’m delighted to find the science behind memento fridge magnets — of which I’ve a lot. In a research revealed in my new favorite journal, Annals of Tourism Analysis, researchers requested 19 Brits with at the least 20 magnets about what their collections meant to them. Magnets “allow the previous to hang-out the current”, conclude the authors. “Each time a fridge door is handed by or opened it will probably fleetingly set off recollections of one other time and place in unplanned and unanticipated methods.”

Please set off our ideas in surprising methods along with your suggestions on this text. Your e-mails are all the time welcome at briefing@nature.com.

Thanks for studying,

Flora Graham, senior editor, Nature Briefing

With contributions by Gemma Conroy and Katrina Krämer

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